I.I. Goriushkin  
  - Objectivization of diagnostics of an alcoholism (gamma-glutamyltransferase and aspartate aminotransferase and alanine aminotransferase)
// In: Горюшкин И.И.  МЕХАНИЗМЫ АЛКОГОЛИЗМА: регуляционно-структурные отношения (патогенез, лечение, диагностика), монография. М.: Спутник+, 2008:75-90.
Горюшкин И.И. - Объективизация диагностики алкоголизма (гамма-глутамилтрасфераза, аспартатаминотрансфераза и аланинаминотрансфераза) - русский ]

          Key words:    biochemical, diagnosic, laboratory, gamma-glutamyltransferase, aspartate aminotransferase, alanine aminotransferase, GGT, AST, ALT

- The sum and substance: 
           I.I. Goriushkin [  - I ask to excuse me for my translation from Russian on English. Later I plan will return to correct  ]


   1._ The purpose of use of laboratory biochemical methods in clinic of an alcoholism is - rising of efficiency of medical-diagnostic process that is reached by means of definition in blood serum of level of activity of transferases: gamma-glutamyltransferase (GGT), aspartate aminotransferase (AST) and alanine aminotransferase (ALT);

   2._ If cases get to group of "practically healthy" persons of "household drunkenness», or the beginning of disease by an alcoholism, or conditions of remission of an alcoholism, - that use of biochemical parameters and «such normal» (for the purpose of specification of the diagnosis an alcoholism) can turn out unproductive;

   3._ The fact of fluctuation (that increases, decreases) ferment indexes of blood serum: the GGT, AST, the ALT, - found out during repeated researches of the patient, carries in itself also acknowledgement of the diagnosis an alcoholism;

   4._ It is important to understand always, that enzymatic laboratory indexes, as well as results of any other clinical research, of course, have real value only in a complex with symptoms.

The bases of these statements
can be seen here:
[ Goriushkin I.I.  "Alcoholism: what is a pathogenetic treatment? A systemic approach"
//Zh Nevrol Psikhiatr Im SS Korsakova 2006;106(4):90-4. Russian (English) ]

       [ Goriushkin I.I.  "Sequence of involving of the ferments presented in blood serum (GGT, AST, ALT) in alcoholic pathogenesis"
// In: Problems of modern narcology: Respublic sbornic nauchni trudov, Moscow, 1991:40-2. Russian]

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[   Copyright © Goriushkin I.I.,
    2008 ( June) - 2010 ( May )  ]

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